Medik8 Crystal Retinal® anti-aging serum, shown with a peach cream smear, is the No.1 retinal serum worldwide and has won over 45 global awards.
A tube of Medik8 Crystal Retinal® is shown upright against a dark background, highlighted as the top retinal serum and winner of 45+ global awards.
A smiling woman applies Crystal Retinal® by Medik8 to her cheek, showcasing its benefits like reducing wrinkles and dark spots while enhancing skin firmness and clarity as the ultimate anti-aging serum.
Before and after comparison of a woman's forehead using Medik8's Crystal Retinal® shows reduced aging signs, with a tube in the corner. Text indicates 97% reported more youthful skin.
A tube of Medik8's Crystal Retinal® on a dark background is surrounded by text highlighting its potency, stability, and outstanding anti-aging results as an alternative to vitamin A serums, revolutionizing skincare with its unique advantages.
A close-up shows a forehead with reduced wrinkles before and after using Medik8's Crystal Retinal®. A tube of the vitamin A serum is displayed, with text claiming 9 out of 10 users prefer this transformative anti-aging solution.
Image displaying six strengths of Medik8's Crystal Retinal® serum, with Retinaldehyde from Strength 1 (0.01%) for sensitive skin to Strength 24 (0.24%) for expert users desiring powerful vitamin A benefits.
A woman in a white coat holds a Medik8 Crystal Retinal® tube, endorsed by a doctor as a vitamin A serum suitable for all skin types, highlighting its effective anti-aging benefits.
A doctor in a white coat smiles while holding Crystal Retinal® by Medik8, praised in text as an effective and innovative retinoid choice.
The skincare routine graphic shows a PM regimen: cleanse, target, apply Medik8's Crystal Retinal® or vitamin A serum, care for eyes, and moisturize. For AM tips, always include sunscreen. Products are elegantly arranged in bottles and tubes on a dark backdrop.
The CSA Philosophy skincare regimen includes Vitamin C serum for brightening, sunscreen for protection, and Medik8 Crystal Retinal® for renewal.
A silver tube of Medik8 Crystal Retinal®, the No.1 anti-ageing serum worldwide and winner of 45+ global awards, featuring a pink cream smear.
A silver tube of Medik8 Crystal Retinal®, the No.1 retinal and vitamin A night serum worldwide with 45+ global awards, alongside a product smear.
A silver tube of Medik8’s Crystal Retinal® is shown with an orange cream smear, award badge, and text stating it's the world’s No. 1 retinal serum, boasting 45+ global awards.
A silver tube of Medik8 Crystal Retinal® vitamin A night serum with an orange smear, labeled the world’s No.1 anti-ageing face serum and winner of 45+ global awards.
A silver tube of Medik8 Crystal Retinal® lies on an orange cream smear, with text marking it as the world’s No.1 anti-ageing serum and winner of over 45 global awards.
Medik8 Crystal Retinal® anti-aging serum, shown with a peach cream smear, is the No.1 retinal serum worldwide and has won over 45 global awards.
A tube of Medik8 Crystal Retinal® is shown upright against a dark background, highlighted as the top retinal serum and winner of 45+ global awards.
A smiling woman applies Crystal Retinal® by Medik8 to her cheek, showcasing its benefits like reducing wrinkles and dark spots while enhancing skin firmness and clarity as the ultimate anti-aging serum.
Before and after comparison of a woman's forehead using Medik8's Crystal Retinal® shows reduced aging signs, with a tube in the corner. Text indicates 97% reported more youthful skin.
A tube of Medik8's Crystal Retinal® on a dark background is surrounded by text highlighting its potency, stability, and outstanding anti-aging results as an alternative to vitamin A serums, revolutionizing skincare with its unique advantages.
A close-up shows a forehead with reduced wrinkles before and after using Medik8's Crystal Retinal®. A tube of the vitamin A serum is displayed, with text claiming 9 out of 10 users prefer this transformative anti-aging solution.
Image displaying six strengths of Medik8's Crystal Retinal® serum, with Retinaldehyde from Strength 1 (0.01%) for sensitive skin to Strength 24 (0.24%) for expert users desiring powerful vitamin A benefits.
A woman in a white coat holds a Medik8 Crystal Retinal® tube, endorsed by a doctor as a vitamin A serum suitable for all skin types, highlighting its effective anti-aging benefits.
A doctor in a white coat smiles while holding Crystal Retinal® by Medik8, praised in text as an effective and innovative retinoid choice.
The skincare routine graphic shows a PM regimen: cleanse, target, apply Medik8's Crystal Retinal® or vitamin A serum, care for eyes, and moisturize. For AM tips, always include sunscreen. Products are elegantly arranged in bottles and tubes on a dark backdrop.
The CSA Philosophy skincare regimen includes Vitamin C serum for brightening, sunscreen for protection, and Medik8 Crystal Retinal® for renewal.
A silver tube of Medik8 Crystal Retinal®, the No.1 anti-ageing serum worldwide and winner of 45+ global awards, featuring a pink cream smear.
A silver tube of Medik8 Crystal Retinal®, the No.1 retinal and vitamin A night serum worldwide with 45+ global awards, alongside a product smear.
A silver tube of Medik8’s Crystal Retinal® is shown with an orange cream smear, award badge, and text stating it's the world’s No. 1 retinal serum, boasting 45+ global awards.
A silver tube of Medik8 Crystal Retinal® vitamin A night serum with an orange smear, labeled the world’s No.1 anti-ageing face serum and winner of 45+ global awards.
A silver tube of Medik8 Crystal Retinal® lies on an orange cream smear, with text marking it as the world’s No.1 anti-ageing serum and winner of over 45 global awards.
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Fine lines & wrinkles

Crystal Retinal®

  • Renew
  • |
  • Firm
  • |
  • Smooth
Award-winning Age-Defying Vitamin A Night Serum

Reveal younger-looking skin with just 1 tube of Crystal Retinal. Our iconic vitamin A night serum is clinically proven to visibly smooth stubborn wrinkles, brighten dark spots, decongest and firm your skin - without irritation.[1]

Crystal Retinal contains retinAL; a next-generation vitamin A which acts 11x faster than standard retinOL.[2] And, unlike others, our patented retinal stability system ensures unmatched retinal potency and effectiveness until the very last drop.

It’s no wonder Crystal Retinal is the UK’s No.1 dermatological face serum.[3]

[1] Proven via independent clinical study on Crystal Retinal 6. Tested on 33 participants over 12 weeks.
[2] G. Siegenthaler et al., Retinol and retinal metabolism, Biochemical Journal, 1990, 268, pp 371-378
[3] Source: Circana (UK) Ltd, Prestige Beauty Retail tracking / Feb 2023 to Jan 2024 / prestige face serum / Dermatologist Brand attribute / Dermatologist Brand is defined as a brand that has identified itself as (i) founded or developed by a dermatologist and/or (ii) is dermatologist recommended / franchise line / value & unit sales. To verify visit: https://www.medik8.com.cy/circana-group-claim-letters

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Reasons to shop Medik8

Free ACS delivery in Cyprus
10% off your first order with newsletter signup
Easy 30 day returns
Key Benefits
Fast Wrinkle Reducing Power

See clinically proven wrinkle reduction with just 1 tube*

*Proven via independent clinical study on Crystal Retinal 6. Tested on 33 participants over 12 weeks.

Radiant, Youthful Skin

Delivers remarkable visible improvement in texture, brightness, firmness & clarity

Customise Your Routine With 5 Progressive Strengths

A retinal strength for beginners to expert users - even sensitive skin

Professional-Grade Results

Retinaldehyde is proven to work up to 11 times faster than classic retinol* - so you can see results sooner

*G. Siegenthaler et al., Retinol and retinal metabolism, Biochemical Journal, 1990, 268, pp 371-378

Effective Results Until the Last Drop

Thanks to Medik8's patented stability complex

Proven Results
BEFORE
AFTER 10 DAYS
BEFORE
AFTER 10 DAYS
97% felt their skin had a more youthful appearance*
20% reduction in the appearance of wrinkles*
20% reduction in visible hyperpigmentation*
11% increase in skin firmness*
100% felt Crystal Retinal was gentle on their skin*
*Proven via independent clinical study on 1 tube of Crystal Retinal 6. Tested on 33 participants over 12 weeks.
How to Use

Step 1

After cleansing in the evening, apply 2 pumps of Crystal Retinal to the face and neck. Allow to absorb then follow with a moisturiser. We recommend Advanced Night Restore which is specifically designed to be used after vitamin A.

Step 2

For new users of Crystal Retinal, phase application in gradually. Use twice a week for the first 2 weeks, every other night for the next 2 weeks, then every night. You should always use a sunscreen the next morning after using vitamin A.

We recommend using at least 1 tube of your current Crystal Retinal strength before moving up the ladder to the next strength.
Available Strengths

Only at Medik8, you can ladder up your visible age-defying results over time with Crystal Retinal's 6 progressive strengths. 

Offering 0.01% - 0.24% retinaldehyde, there’s a strength for everyone; from very sensitive skins to expert users. 

Take our easy quiz to find your strength. 

Guide to Layering
Step 1: Cleanse
Medik8
Morning
Evening
Surface Radiance Cleanse™
Select a Size
Step 2: Target
The Medik8 Cyprus Liquid Peptides Advanced MP serum comes in a black bottle with a pump and is surrounded by four 2025 beauty award badges, promising noticeable wrinkle reduction and a filler-like effect.
Morning
Evening
Liquid Peptides Advanced MP
30ml
Step 3: Renew
Medik8 Crystal Retinal® anti-aging serum, shown with a peach cream smear, is the No.1 retinal serum worldwide and has won over 45 global awards.
Evening
Crystal Retinal®
Select a Strength
Step 4: Moisturise
A 50mL jar of Medik8
Evening
Advanced Night Restore™
Select a Size
Key Ingredients
Retinaldehyde

Proven to work up to 11 times faster than standard retinol,* retinaldehyde (retinal for short) is a revolutionary form of vitamin A that effectively targets the appearance of fine lines and wrinkles, hyperpigmentation, uneven skin texture and loss of firmness - without irritation.

*G. Siegenthaler et al., Retinol and retinal metabolism, Biochemical Journal, 1990, 268, pp 371-378

Hyaluronic Acid

With the ability to attract and retain more than 1,000 times its own weight in water, hyaluronic acid draws moisture into the upper layers of the skin; leaving the complexion hydrated and visibly supple.

Vitamin E

A powerful antioxidant, vitamin E works to protect against the ageing effects of free radical damage while stabilising retinal for optimal power.

Glycerin

A natural humectant which traps moisture within the skin to leave it hydrated and comfortable.

Vitamin E

A powerful antioxidant, vitamin E works to protect against the ageing effects of free radical damage while stabilising retinal for optimal power.

Glycerin

A natural humectant which traps moisture within the skin to leave it hydrated and comfortable.

Full List of Ingredients
Crystal Retinal®
Award-winning Age-Defying Vitamin A Night Serum

Aqua (Water), Caprylic/Capric Triglyceride, Glycerin, Isododecane, Cetearyl Olivate, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Cetearyl Alcohol, PPG-12/SMDI Copolymer, Sorbitan Olivate, Tocopheryl Acetate, Titanium Dioxide, Eclipta Prostrata Extract, Cyclodextrin, Squalane, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Phenoxyethanol, Melia Azadirachta Leaf Extract, Hydroxypropyl Methylcellulose, Sodium Hyaluronate, Tetrahexyldecyl Ascorbate, Rubus Chamaemorus (Cloudberry) Seed Oil, Alumina, Isostearic Acid, Lecithin, Polyglyceryl-3 Polyricinoleate, Polyhydroxystearic Acid, Stearic Acid, Pentylene Glycol, Retinal, Moringa Oleifera Seed Oil, Sodium Polyaspartate, Climbazole, Disodium EDTA, Lonicera Japonica (Honeysuckle) Flower Extract, Lonicera Caprifolium (Honeysuckle) Flower Extract, Daucus Carota Sativa (Carrot) Seed Oil, Ethylhexylglycerin, 3-O-Ethyl Ascorbic Acid, Dipteryx Odorata (Tonka) Bean Extract, Hydroxyacetophenone, Polysorbate 60, Sorbitan Isostearate, Vanilla Planifolia (Vanilla) Fruit Extract, Decylene Glycol, 1,2-Hexanediol, BHT, Coumarin.

*Although we try our best to ensure this list of ingredients is accurate there may be product upgrades from time to time, or slight variants between different regions based on local laws, meaning the only definitive ingredient list is that which is printed on the product packaging.
  • Clinically-proven formula
  • Dermatologist recommended
  • No artificial fragrance
  • No synthetic colours
  • Alcohol free
  • Certified by the vegan society
Experts Recommended

I swear by Medik8's Crystal Retinal Range - especially for nighttime use

DR. JUSTINE KLUK
Consultant Dermatologist

Really helps keep skin smooth, while tackling fine lines.

NADINE BAGGOTT
Skincare Expert & Beauty Journalist

Complete Your Regime

Reviews

Frequently Asked Questions

When should I apply Crystal Retinal?
You should apply Crystal Retinal as part of your evening skincare routine - after cleanser, toner and serums, but before your moisturiser.
Can I use Crystal Retinal every night?
As long as you build your use up gradually and start with the appropriate strength to begin with, you can use Crystal Retinal every night. For new users of Crystal Retinal, we strongly recommend that you phase-in application to enable your skin to build up a tolerance while avoiding any potential irritation. Use twice a week for the first two weeks, every other night for the following two weeks, then every night.
Can I use Crystal Retinal while pregnant or breastfeeding?
As a cosmetics company, we are unable to provide product advice in relation to medical conditions such as pregnancy or breastfeeding. We strongly recommend discussing the ingredients with your GP or midwife before use. We do, however, generally recommend avoiding vitamin A use while pregnant or breastfeeding, which is why we offer a plant-based vitamin A alternative - Bakuchiol Peptides.
Do I need to follow Crystal Retinal with a moisturiser?
We do recommend applying a moisturiser after vitamin A. Our bestselling night cream, Advanced Night Restore, is specifically designed to be used following vitamin A use. It helps to boost the visible age-defying benefits of vitamin A while maintaining optimal comfort.
Can I use Crystal Retinal around my eye area?
We don't recommend using Crystal Retinal directly around the eye area due to its very delicate nature. However, that's exactly why we've created Crystal Retinal Ceramide Eye. It boasts all of the renowned age-defying power of our original Crystal Retinal, but is expertly optimised for specific use on the delicate eye area.
How do I use Crystal Retinal alongside vitamin C?
We recommend using vitamin C alongside Crystal Retinal (vitamin A) as part of our pioneering CSA Philosophy. This simple yet clinically proven skincare approach champions vitamin C plus Sunscreen by day, vitamin A (retinoids) by night as the secret to youthful, glowing skin. After cleansing in the morning, apply your vitamin C serum (such as C-Tetra Luxe) and follow with your sunscreen (we recommend Advanced Day Ultimate Protect). After cleansing in the evening, apply Crystal Retinal.
Can I use Crystal Retinal around my eye area?
We don't recommend using Crystal Retinal directly around the eye area due to its very delicate nature. However, that's exactly why we've created Crystal Retinal Ceramide Eye. It boasts all of the renowned age-defying power of our original Crystal Retinal, but is expertly optimised for specific use on the delicate eye area.
How do I use Crystal Retinal alongside vitamin C?
We recommend using vitamin C alongside Crystal Retinal (vitamin A) as part of our pioneering CSA Philosophy. This simple yet clinically proven skincare approach champions vitamin C plus Sunscreen by day, vitamin A (retinoids) by night as the secret to youthful, glowing skin. After cleansing in the morning, apply your vitamin C serum (such as C-Tetra Luxe) and follow with your sunscreen (we recommend Advanced Day Ultimate Protect). After cleansing in the evening, apply Crystal Retinal.
Crystal Retinal®
(Beginner)
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