Crystal Retinal: Clinical Claims

Reveal younger-looking skin with just 1 tube of Crystal Retinal.[2] This iconic vitamin A night serum contains next-generation retinAL, clinically proven to act 11x faster than standard retinOL[3] to visibly smooth, brighten, decongest and firm your skin.

20%

Reduction in visible dark wrinkles & dark spots[2]

97%

Felt their skin looked more youthful[2]

11%

Improvement in skin firmness[2]

100%

Agree Crystal Retinal is gentle [2]

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New: Crystal Retinal 24

Stronger, faster wrinkle reduction in just 1 tube. [7]

9/10 agree it's the most powerful & effective anti-ageing retinoid they have ever used. [7]

97% experienced no irritiation when moving up the ladder. [8]

93% agree that their results improved as they moved up the ladder. [8]

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97% agree Crystal Retinal is the most powerful anti-ageing product they have ever used[4]

Proven to leave skin visibly smoother in 7 days[4]

Proven to leave skin visibly brighter in 7 days[4]

Proven to leave skin visibly clearer in 7 days[4]

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The closest thing to prescription-strength retinoic acid, without needing a prescription.

100% agreed skin felt hydrated after use[5]

Proven to not cause retinisation on sensitive skins

100% did not experience irritation after 4 week phase-in[2]

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Clinically proven to improve wrinkle reduction as you move up the Crystal Retinal ladder

97% agree no new wrinkles appeared while moving up the Crystal Retinal ladder[4]

96% agree the Crystal Retinal ladder is easy to navigate[6]

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A tube of Medik8 Crystal Retinal® with serum smears, an award badge, and text reading “UK’s No.1 Dermatological Face Serum” and “World First Patented Technology.”.

Crystal Retinal 1

Award-winning Age-Defying Vitamin A Night Serum

30ml / €56
Medik8 Crystal Retinal® tube with a product swatch, award badge, and text showcasing its advanced technology and status as the UK’s No.1 dermatological vitamin A night serum.

Crystal Retinal 3

Award-winning Age-Defying Vitamin A Night Serum

30ml / €65
Medik8 Crystal Retinal® tube with cream smear, featuring award badges and text highlighting it as the UK’s No.1 dermatological anti-ageing serum and winner of the Get the Gloss Beauty Awards 2025.

Crystal Retinal 6

Award-winning Age-Defying Vitamin A Night Serum

30ml / €82
A silver tube of Medik8 Crystal Retinal®, the UK's No.1 dermatological face serum, is pictured with a product swatch and award badge.

Crystal Retinal 10

Award-winning Age-Defying Vitamin A Night Serum

30ml / €110
A tube of Medik8 Crystal Retinal®, the UK’s No.1 dermatological retinal serum, with award badges and an orange cream smear in the background—ideal for your anti-aging skincare routine.

Crystal Retinal 20

Award-winning Age-Defying Vitamin A Night Serum

30ml / €125
Medik8 Crystal Retinal® face serum tube with orange swatch, award and technology badges, featuring text: UK’s No.1 dermatological face serum for anti-aging skincare.

Crystal Retinal 24

Award-winning Age-Defying Vitamin A Night Serum

30ml / €135

[2] Proven via independent clinical study on Crystal Retinal 6. Tested on 33 participants over 12 weeks

[3] G. Siegenthaler et al., Retinol and retinal metabolism, Biochemical Journal, 1990, 268, pp 371-378

[4]Proven via independent clinical study on the Crystal Retinal ladder tested on 30 participants over 24 weeks

[5] Proven via multiple independent clinical & consumer studies, including testing on sensitive skin

[6] Based on feedback from 147 verified Crystal Retinal customers

[7] Proven via independent clinical study on the Crystal Retinal ladder tested on 30 participants over 24 weeks.

[8] - Proven via independent clinical study on the Crystal Retinal ladder tested on 30 participants over 18 weeks.