A white bottle of Medik8 r-Retinoate® Day & Night with a pump dispenser. This anti-ageing skincare product is labelled for day and night use, features patented technology, and uses retinyl retinoate to help achieve youthful skin.
A white bottle of Medik8 r-Retinoate® Day & Night is displayed, featuring text about its three age-defying technologies: Retinyl Retinoate, Vitamin C, and Hyaluronic Acid for youthful skin. Perfect for those seeking advanced anti-ageing skincare.
A bottle of Medik8 r-Retinoate® Day & Night with the text "Can be used both day & night for accelerated anti-ageing skincare results" next to it.
Close-up of a Medik8 r-Retinoate® Day & Night bottle alongside a cream sample and the text "8x more powerful than standard retinol" on a light gray background, perfect for achieving youthful skin with its potent anti-ageing skincare formula.
Person holding a bottle of Medik8 r-Retinoate® Day & Night, with text "Powerful results, even on sensitive skin" in the foreground. This anti-ageing skincare product promotes youthful skin through the power of retinyl retinoate.
Image showing text "Featuring r-Retinoate® Day & Night, patented & exclusive to Medik8, a super molecule fusing Retinol and Retinoic Acid for youthful skin" over a background of a white, cream-like texture.
r-Retinoate® Day & Night by Medik8. A Youth Activating Cream Day & Night.

r-Retinoate® Day & Night

Youth Activating Cream Day & Night

r-Retinoate® Day & Night

Free & Fast Delivery in Cyprus with ACS

A luxe multi-step serum featuring retinyl retinoate, a pioneering derivative of vitamin A. r-Retinoate Day & Night interlaces revolutionary science with a sublime formulation, to create a sensorial experience with visible anti-ageing results.

Up to 2 months supply from 1 bottle when used twice a day.

Now upgraded with an enhanced level of vitamin C

Skin looks clearer, brighter and revitalised; ultimately more youthful. Improvements become even more remarkable over time with continued use.
Improved visible tone, texture and skin radiance. The complexion is left illuminated and gifted with a silken touch.
Key Ingredients
Patented, encapsulated retinyl retinoate, exclusive to Medik8.

Tetrahexyldecyl Ascorbate (Vitamin C), Hyaluronic Acid & Vitamin E
r-Retinoate® Day & Night

A true breakthrough in anti-ageing skincare

8x more powerful than retinol

Medik8 exclusive retinyl retinoate is proven to be 8x more powerful than retinol[1], yet highly tolerated even by the most sensitive skin.

Luxe Multi-Step Serum

r-Retinoate combines vitamin A with tetrahexyldecyl ascorbate, a stabilised, gentle form of vitamin C. Enhancing visible skin luminosity, as well as antioxidant protection, vitamin A and C steps are now intertwined.*

*r-Retinoate Day & Night now features the equivalent level of vitamin C in C-Tetra serum.

Morning Vitamin A

Retinyl retinoate is photostable, meaning it doesn’t break down in sunlight like traditional forms of vitamin A. This means you can use it confidently both morning and night.

Perfect Product Pair

Looking for intensified results? Layer r-Retinoate Day & Night underneath r-Retinoate Intense for the ultimate in bright, youthful-looking skin.

How to use it

  • How to Apply

    After cleansing in the morning and evening, blend r-Retinoate Day & Night evenly across face, neck and décolletage. You should always use a sunscreen in the morning while using vitamin A.

  • Routines & Layering

    r-Retinoate Day & Night features in our carefully curated regime guide Luxe Age Repair. Click the link for additional product recommendations and easy-to-follow layering advice.

  • Patch Testing

    Patch testing prior to use is advised. Refer to medik8.co/patch for an in-depth guide to patch testing.

Key Ingredients

Our ingredient choices—the forms, what we include, and what we don't—are all made based on what you really need.

  • Retinyl Retinoate

    Patented, encapsulated retinyl retinoate, exclusive to Medik8. 8 times more powerful than retinol[1] this non-irritating vitamin A helps to stimulate collagen synthesis and supports the regeneration of skin cells.

    [1] H. Kim et al., Synthesis and in vitro biological activity of retinyl retinoate, a novel hybrid retinoid derivative, Bioorganic & Medicinal Chemistry, 2008, 15;16(12), pp 6387-93

  • Tetrahexyldecyl Ascorbate

    An exceptional antioxidant, this stabilised form of vitamin C protects the skin from harmful free radicals while helping to support the production of collagen for a youthful, brighter-looking complexion.

  • Hyaluronic Acid

    With a unique ability to attract and retain more than 1,000 times its own weight in water, hyaluronic acid draws moisture from the air into the skin to provide intense hydration.

  • Vitamin E

    A lipid-soluble antioxidant that is naturally present in the skin, vitamin E helps to protect the skin from free radicals and boosts the power of vitamin C for optimum effect and results.

What we choose not to include

  • No Artificial Fragrance
  • No Synthetic Colours
  • No Phthalates
  • Paraben Free
  • Alcohol Free
Full Ingredients

Hear from the experts

“Retinyl retinoate is one of the only forms of vitamin A which is active in sunlight; able to be used in both the morning and the evening. That means you can get vitamin A benefits at both ends of the day. Retinyl retinoate is particularly great for protecting our delicate collagen molecules from degrading in UV light. With enhanced levels of vitamin C in r-Retinoate Day & Night, we also protect the skin from harmful free radical damage.”

Daniel Isaacs
Director of Research


Professional treatments

  • Boost the results of r-Retinoate

    Get a detailed skin consultation and experience one of our relaxing anti-ageing facial treatments.

  • Rewind Professional Skin Peel

    A targeted peel that helps to promote collagen production to reduce the appearance of fine lines and wrinkles. It fades away imperfections, leaving the skin visibly smoothed and rejuvenated.

Get a Consultation