A white bottle of Medik8 r-Retinoate® Day & Night cream, containing retinyl retinoate and vitamin A, comes with a pump dispenser and is pictured next to a swirl of the anti-aging serum.
A woman applies Medik8's r-Retinoate® Day & Night skincare serum, a 3-in-1 formula that brightens, revitalizes, smooths, and improves skin tone. Comparable to retinol, it features retinyl retinoate for enhanced anti-aging benefits and vitamin A for radiant skin.
Medik8's r-Retinoate® Day & Night serum on a marble surface, highlighting its anti-aging power with encapsulated retinyl retinoate, stabilized vitamin C, and hyaluronic acid.
The image shows three r-Retinoate® Medik8 skincare products: Day & Night, Day & Night Eye Serum, and Intense, showcasing retinyl retinoate's power on an elegant reflective surface.
Infographic showing a skincare routine: AM - Cleanse, tone, use Vitamin C + Medik8 r-Retinoate® Day & Night serum, sunscreen. PM - Cleanse, tone, apply Vitamin C + r-Retinoate® for rejuvenation, then moisturize.
A bottle of Medik8's r-Retinoate® Day & Night, enriched with retinyl retinoate vitamin A, stands elegantly before its box. The minimalistic design features molecular graphics, mirroring its advanced anti-aging serum formula.
A white bottle of Medik8 r-Retinoate® Day & Night cream, containing retinyl retinoate and vitamin A, comes with a pump dispenser and is pictured next to a swirl of the anti-aging serum.
A woman applies Medik8's r-Retinoate® Day & Night skincare serum, a 3-in-1 formula that brightens, revitalizes, smooths, and improves skin tone. Comparable to retinol, it features retinyl retinoate for enhanced anti-aging benefits and vitamin A for radiant skin.
Medik8's r-Retinoate® Day & Night serum on a marble surface, highlighting its anti-aging power with encapsulated retinyl retinoate, stabilized vitamin C, and hyaluronic acid.
The image shows three r-Retinoate® Medik8 skincare products: Day & Night, Day & Night Eye Serum, and Intense, showcasing retinyl retinoate's power on an elegant reflective surface.
Infographic showing a skincare routine: AM - Cleanse, tone, use Vitamin C + Medik8 r-Retinoate® Day & Night serum, sunscreen. PM - Cleanse, tone, apply Vitamin C + r-Retinoate® for rejuvenation, then moisturize.
A bottle of Medik8's r-Retinoate® Day & Night, enriched with retinyl retinoate vitamin A, stands elegantly before its box. The minimalistic design features molecular graphics, mirroring its advanced anti-aging serum formula.
1 / 7
Fine lines & wrinkles

r-Retinoate® Day & Night

  • Brighten
  • |
  • Smooth
  • |
  • Revive
Youth Activating Cream

Our remarkable vitamin A that can be used both day and night for faster visible brightening, revitalising and smoothing results while remaining gentle.

This luxurious serum is powered by Medik8-exclusive encapsulated retinyl retinoate - proven to be 8x more powerful than standard retinol* in delivering age-defying benefits.

The multi-step-in-one formula combines retinyl retinoate with stabilised vitamin C and hyaluronic acid for profound visible improvement in skin tone, texture and radiance.

r-Retinoate Day & Night interlaces revolutionary science with a sublime sensorial experience that's highly tolerated by the most sensitive skin.

*H. Kim et al., Synthesis and in vitro biological activity of retinyl retinoate, a novel hybrid retinoid derivative, Bioorganic & Medicinal Chemistry, 2008, 15;16(12), pp 6387-93
Full Size (50ml)
Earn points
Reward Points

Earn 1 point for every €1 spent with our rewards programme, Me&Medik8. Simply create an account to join. Collect points every time you shop and redeem them for rewards, including money off future purchases.

You can also enjoy lots of exclusive benefits from secret promotions, free shipping and a gift on your birthday.

Earn points today! Join Me&Medik8 Rewards to earn points when you shop this product. Log In or Sign Up

Reasons to shop Medik8

Free ACS delivery in Cyprus
10% off your first order with newsletter signup
Easy 30 day returns
A sleek black bottle of Medik8 r-Retinoate® Intense, enriched with Vitamin A for potent wrinkle reduction, rests beside a luxurious cream smear on a pristine white background.
r-Retinoate® Intense
  • Rejuvenate
  • |
  • Firm
  • |
  • Brighten
 Intense Youth Activating Cream
Full Size (50ML)
Key Benefits
Accelerated Age-Defying Results, Day & Night

Uniquely photostable retinyl retinoate doesn't lose its power in sunlight so delivers visible illuminating, smoothing & revitalising benefits both morning & night.

3-in-1 Time-Saver

Delivers all the visible wrinkle-smoothing, brightening & hydrating benefits of vitamin A, vitamin C and hyaluronic acid in one luxurious formula.

8x Stronger Than Retinol

Medik8-exclusive encapsulated retinyl retinoate is proven to be gentle yet 8x more powerful than standard retinol* in delivering visible results.



*H. Kim et al., Synthesis and in vitro biological activity of retinyl retinoate, a novel hybrid retinoid derivative, Bioorganic & Medicinal Chemistry, 2008, 15;16(12), pp 6387-93

How to Use

Step 1

After cleansing in the evening, massage 2 pumps of r-Retinoate Day & Night evenly across face, neck and décolletage.

NOTE

You should always use a sunscreen the morning after using vitamin A.

Guide to Layering
Step 1: Cleanse
A bottle of Lipid-Balance Cleansing Oil™ by Medik8, surrounded by oil droplets. The 140ml (4.7 fl. oz) bottle with a pump features innovative anti-pollution technology, effortlessly removing makeup while nourishing your skin.
Morning
Evening
Lipid-Balance Cleansing Oil™
Full Size (140ml)
Step 2: Cleanse
A white bottle of Medik8
Morning
Evening
Micellar Mousse™
Full Size (150ml)
Step 3: Target
A white bottle of Medik8 r-Retinoate® Day & Night cream, containing retinyl retinoate and vitamin A, comes with a pump dispenser and is pictured next to a swirl of the anti-aging serum.
Morning
Evening
r-Retinoate® Day & Night
Full Size (50ml)
Key Ingredients
Encapsulated Retinyl Retinoate

Patented and exclusive to Medik8, this unique vitamin A molecule is the breakthrough result of 8 years of expert research. Retinyl retinoate is proven to be 8x more powerful than classic retinol* in delivering astonishing age-defying results.

*H. Kim et al., Synthesis and in vitro biological activity of retinyl retinoate, a novel hybrid retinoid derivative, Bioorganic & Medicinal Chemistry, 2008, 15;16(12), pp 6387-93

14% Stabilised Vitamin C (tetrahexyldecyl ascorbate)

A low-irritation form of vitamin C that delivers exceptional antioxidant protection against harmful free radical damage while supporting collagen production for a visibly even, more youthful-looking complexion.

Hyaluronic Acid

With the ability to attract and retain more than 1,000 times its own weight in water, hyaluronic acid draws moisture into the upper layers of the skin; leaving the complexion hydrated and visibly supple.

Vitamin E

A powerful antioxidant that provides additional antioxidant protection against the ageing effects of free radicals. It also helps to boost the power of vitamin C for optimum visible results.

Hyaluronic Acid

With the ability to attract and retain more than 1,000 times its own weight in water, hyaluronic acid draws moisture into the upper layers of the skin; leaving the complexion hydrated and visibly supple.

Vitamin E

A powerful antioxidant that provides additional antioxidant protection against the ageing effects of free radicals. It also helps to boost the power of vitamin C for optimum visible results.

Full List of Ingredients
r-Retinoate® Day & Night
Youth Activating Cream

Aqua (Water), Tetrahexyldecyl Ascorbate, Heptyl Undecylenate, Caprylic/Capric Triglyceride, Methylpropanediol, Polylactic Acid, Cetearyl Olivate, Sodium Polyacryloyldimethyl Taurate, Cetearyl Isononanoate, Distarch Phosphate, Tocopheryl Acetate, Sorbitan Olivate, Hydrogenated Polydecene, Retinyl Retinoate, Glycerin, Caprylyl Glycol, Sodium Hyaluronate, Cholesteryl Nonanoate, Disodium EDTA, Hydroxyacetophenone, Canola Oil, Cetearyl Alcohol, Phenylpropanol, Vanilla Planifolia (Vanilla) Fruit Extract, 3-O-Ethyl Ascorbic Acid, Sodium Metabisulfite, BHT, Sodium Hydroxide, Trideceth-10.

*Although we try our best to ensure this list of ingredients is accurate there may be product upgrades from time to time, or slight variants between different regions based on local laws, meaning the only definitive ingredient list is that which is printed on the product packaging.
  • No artificial fragrance
  • No synthetic colours
  • Paraben free
  • Alcohol free
Experts Recommended

It’s easy to see why this moisturiser counts Hailey Bieber as one of its fans!

TRACY ACHONWA
Beauty Writer - British Vogue

Love this product. Don’t think I can live without it!

MEGAN S
Verified Medik8 Customer

Complete Your Regime

Reviews

Frequently Asked Questions

Can I use r-Retinoate Day & Night if I'm pregnant or breastfeeding?
As a cosmetics company, we are unable to provide product advice in relation to medical conditions such as pregnancy or breastfeeding. We strongly recommend discussing the ingredients with your GP or midwife before use. We do, however, generally recommend avoiding vitamin A use while pregnant or breastfeeding, which is why we offer a plant-based vitamin A alternative - Bakuchiol Peptides.
How and when should I apply r-Retinoate Day & Night?
r-Retinoate Day & Night can be applied both day and night. After cleansing, massage 2 pumps evenly across the face, neck and décolletage.
At what age can I start to use this product?
All of our products are suitable for those aged 16+ - including r-Retinoate Day & Night.
Do I need to use a moisturiser on top of r-Retinoate Day & Night?
We would recommend using a moisturiser on top of r-Retinoate Day & Night as this formula is a creamy-textured serum, designed to be layered under a moisturiser morning and/or night.
r-Retinoate® Day & Night
Full Size (50ml)
Full Size (50ml)