Exo-PDRN Prismatic+

  • Rejuvenate
  • |
  • Plump
  • |
  • Illuminate
Youthful Vitality Serum with Prismatic PDRN & Triple Exosome Complex

Boost skin’s natural rejuvenation by +50%[1] with Exo-PDRN Prismatic+, a next-generation PDRN serum rooted in real skin biology. Designed to support the skin’s key natural pathways, helping to restore visible vitality, refine tone and texture, boost luminosity and support calm, resilient-looking skin.

Central to the formula is our Rejuvenation Blueprint, built to address the 3 Rs of Rejuvenation: Recover, Restore and Recharge. This complete skin system delivers a multi-dimensional approach to visible vitality.

Prismatic PDRN helps provide essential building blocks to support and aid in optimal skin recovery and calm visible redness. A highly concentrated triple exosome complex, featuring up to 151 billion exosomes per bottle, and our breakthrough GF MiniProteinTM visibly restores by supporting skin’s natural signalling processes that facilitate skin resilience and reinforce the skin barrier.  An ATP Precursor helps recharge the skin’s natural processes involved in visible rejuvenation, for a smoother, more revitalised complexion.

Earn points
Reward Points

Earn 1 point for every €1 spent with our rewards programme, Me&Medik8. Simply create an account to join. Collect points every time you shop and redeem them for rewards, including money off future purchases.

You can also enjoy lots of exclusive benefits from secret promotions, free shipping and a gift on your birthday.

Earn points today! Join Me&Medik8 Rewards to earn points when you shop this product. Log In or Sign Up

Reasons to shop Medik8

Free ACS delivery in Cyprus
10% off your first order with newsletter signup
Easy 30 day returns
Key Benefits
Visible Skin Rejuvenation

Scientifically proven to boost the skin’s natural rejuvenation by over 50%.[1]

Refined Tone & Texture

Supports visibly smoother skin with improved tone and texture.

Optimal Skin Recovery Support

Designed to support the skin’s natural recovery processes, making it ideal for daily use and alongside professional treatments.

Restored Vitality & Luminosity

Clinically proven to improve the look of skin luminosity and vitality in 7 days.[2]

Visibly Calm, Resilient-Looking Skin

Clinically proven to improve skin barrier function in 7 days.[2]

Proven Results
BEFORE
AFTER
BEFORE
AFTER
+50% boost in natural skin rejuvenation⁽¹⁾
7 days to improved skin barrier function⁽²⁾
7 days to improved skin luminosity⁽²⁾
7 days to visibly improved skin volume⁽²⁾
7 days to improved skin tone⁽²⁾
14 days to visibly improved wrinkles⁽²⁾
14 days to improved firmness⁽²⁾
100% agree this is the perfect post-procedure partner for their in-clinic PDRN treatment⁽³⁾
98% agree the results continue to get better with time⁽³⁾
[1] Proven via ex vivo study measuring Ki67 protein marker for cell proliferation vs. untreated control after 24 hours. [2] Proven via independent clinical study on Exo-PDRN Prismatic+ on 60 volunteers over 1 week. [3] Proven via independent consumer study conducted over 4 weeks on 52 participants who had received injectable polynucleotide treatments within a week of the study. [4] Proven via in vitro skin penetration study versus salmon and rose PDRN benchmarks.
How to Use

If you're new to Exo-PDRN Primastic+, we recommend a patch test at least 24 hours before first use. Learn how to patch test here.

After cleansing in the morning and evening, apply 1-2 pumps of Exo-PDRN
Prismatic+  evenly across the face, neck & décolletage. Use light upward strokes and allow to fully absorb.

Guide to Layering
Step 1: Cleanse
Medik8
Morning
Evening
Surface Radiance Cleanse™
Select a Size
Step 2: Target
A white bottle of Medik8 Cyprus Exo-PDRN Prismatic+ serum with a pump dispenser, set against a backdrop of soft rainbow lighting.
Morning
Evening
Exo-PDRN Prismatic+
30ML
Step 3: Brighten
A bottle of Medik8 Cyprus C-Tetra® Advanced vitamin C serum with pump, product drops, an award badge, and a "0% Barrier Disruption" badge on a white background for skin brightening and anti-ageing.
Morning
C-Tetra® Advanced
30ml
Step 4: Moisturise
A white jar labeled "Advanced Pro-Collagen+ Peptide Cream" by Medik8 Cyprus, filled with white cream. Highlights include growth factors, NAD+ longevity booster, and anti-aging benefits for firmer skin.
Morning
Evening
Advanced Pro-Collagen+ Peptide Cream
Select a SIZE
Step 5: Protect
A white tube of Medik8
Morning
Advanced Day Ultimate Protect™
Full Size (50ml)
Key Ingredients
Prismatic PDRN

A pioneering form of vegan (contains no animal derrived ingredients) PDRN with a stable tetrahedral structure for 100% better skin absorption than traditional PDRN.[4] Composed of DNA particles that penetrate 61% deeper than traditional PDRN[4] to support skin recovery, help soothe visible irritation and reveal smoother, more youthful-looking skin.

Triple Exosome Complex

Designed to support natural skin signalling processes, resilience and recovery, helping to strengthen the skin barrier and promote a healthier, more radiant-looking complexion.

GF MiniProteinTM

Visibly improves the appearance of skin structure over time by helping to boost skin’s collagen, elastin & hyaluronic acid levels.

ATP Precursor

An energy-carrying molecule that helps optimise the natural processes involved in visible skin rejuvenation.

GF MiniProteinTM

Visibly improves the appearance of skin structure over time by helping to boost skin’s collagen, elastin & hyaluronic acid levels.

ATP Precursor

An energy-carrying molecule that helps optimise the natural processes involved in visible skin rejuvenation.

Full List of Ingredients
Exo-PDRN Prismatic+
Youthful Vitality Serum with Prismatic PDRN & Triple Exosome Complex

Aqua (Water), Glycerin, Niacinamide, Lactobacillus Ferment, Centella Asiatica Leaf Extract, Lactobacillus Extracellular Vesicles, DNA, Punica Granatum Extract, Laminaria Digitata Extract, Oligopeptide-1, Disodium Adenosine Triphosphate, Sodium Hyaluronate, Lysine HCl, Proline, Histidine HCl, Arginine, Threonine, Serine, Valine, Alanine, Panthenol, Glutamic Acid, Leucine, Glycine, Taurine, Allantoin, Isoleucine, Phenylalanine, Polyacrylate Crosspolymer-6, Magnesium Aspartate, Butylene Glycol, Citric Acid, Calcium Pantothenate, Ethylhexylglycerin, 1,2-Hexanediol, Pentylene Glycol, Benzyl Alcohol, Caprylyl Glycol, Dehydroacetic Acid, Phenoxyethanol, Sodium Citrate

*Although we try our best to ensure this list of ingredients is accurate there may be product upgrades from time to time, or slight variants between different regions based on local laws, meaning the only definitive ingredient list is that which is printed on the product packaging.
  • clinically proven
  • fragrance-free
  • Dermatologically tested
  • Proven gentle formula
  • certified by the vegan society
Experts Recommended

Exo-PDRN Prismatic+ reflects our belief that visible rejuvenation comes from supporting the skin’s inherent biology. We engineered a formula that works with the natural processes skin relies on to recover and function at its best. By addressing Recover, Restore and Recharge together, we help create the optimal conditions for skin to look healthier and visibly rejuvenated.

Daniel Isaacs
Chief Product Officer & Founding Partner of Medik8

Exo-PDRN Prismatic+ reflects our belief that visible rejuvenation comes from supporting the skin’s inherent biology. We engineered a formula that works with the natural processes skin relies on to recover and function at its best. By addressing Recover, Restore and Recharge together, we help create the optimal conditions for skin to look healthier and visibly rejuvenated.

Cristiana, 40
Verified Medik8 Trial Participant

My skin feels transformed. It looks younger, brighter and more even than ever before.

Nas, 40
Verified Medik8 Trial Participant

Others have noticed and commented. My face is smoother and brighter and I find myself needing to put on less makeup to feel confident.

Jane, 44
Verified Medik8 Trial Participant

Find Your Serum

Reviews

Frequently Asked Questions

Does the Exo-PDRN Prismatic+ contain fragrance?
No. Exo-PDRN Prismatic+ is fragrance-free, making it suitable for even the most sensitive skin types.
Has it been tested on all skin types?
Yes. Exo-PDRN Prismatic+ has been tested on all skin types.
Is it suitable for sensitive skin?
Yes. Exo-PDRN Prismatic+ is designed to be gentle and suitable for sensitive skin.
Can I use it with makeup?
Yes. Exo-PDRN Prismatic+ has been tested to layer seamlessly under makeup, making it ideal for everyday use.
Why are you not using spicules like other exosome serums on the market?
Spicules work by creating micro-channels through controlled micro-trauma. We chose not to include spicules as that can be unnecessarily harsh on post-treatment skin. Instead, Exo-PDRN Prismatic+ uses a carefully engineered combination of advanced ingredients to deliver results in a gentler, more comfortable way, without placing unnecessary stress on the skin.
Should I choose Exo-PDRN or Liquid Peptides Advanced MP?
Both formulas are powerhouses and although there are slight overlaps, they focus on different skin goals. They also complement each other perfectly and can be used together in the same routine. Choose Liquid Peptides Advanced MP if your main goal is line-smoothing. It uses dual MiniProteins™ supported by a concentrated peptide complex to specifically target expression lines and build visible wrinkle reduction over time.  Choose Exo-PDRN Prismatic+ if your skin needs comprehensive rejuvenation and vitality. It focuses on recovery and uses next generation PDRN technology and exosomes to support the skin barrier and restore a healthy glow. If you decide to incorporate both into your routine, we recommend layering from thinnest to thickest consistency. In this case, apply Exo-PDRN Prismatic+ first, followed by Liquid Peptides Advanced MP, both morning and evening.
Can I use Exo-PDRN Prismatic+ with Liquid Peptides Advanced MP?
Absolutely. Exo-PDRN Prismatic+ and Liquid Peptides Advanced MP make an ideal age-defying duo. Use Liquid Peptides Advanced MP to target expression lines and build visible wrinkle reduction and Exo-PDRN Prismatic+ to support long-term skin rejuvenation, resilience and recovery.
Can I use it with sunscreen?
Absolutely. Its lightweight texture is designed to layer well under sunscreen, making it suitable for both morning and evening routines.
Can I use Exo-PDRN Prismatic+ with exfoliating acids?
Yes. Exo-PDRN Prismatic+ can be applied after exfoliating acids. We recommend following with a moisturiser to help support the skin barrier and minimise the risk of any dryness.
Is Exo-PDRN Prismatic+ suitable for dry skin?
Yes. The formula contains hydrating and soothing ingredients, making it suitable for dry skin. Due to its water-light texture, we recommend following with a moisturiser for optimal comfort and results.
Is Exo-PDRN Prismatic+ suitable for oily skin?
Yes. Exo-PDRN Prismatic+ is oil-free and suitable for oily skin types. It delivers an instant healthy glow without leaving skin looking shiny.
Can I use Exo-PDRN Prismatic+ with C-Tetra Advanced?
Absolutely. Exo-PDRN Prismatic+ and C-Tetra Advanced make an ideal duo to help improve the skin’s natural recovery mechanisms. Use C-Tetra Advanced to defend against premature skin ageing and achieve accelerated visible skin brightening, and Exo-PDRN Prismatic+ to support long-term skin rejuvenation, resilience and recovery.
Does the 'GF' in GF MiniProtein™ (found in Liquid Peptides Advanced MP, Advanced Pro-Collagen+ Peptide Cream, and Exo-PDRN Prismatic+) stand for Growth Factor?
Yes, the 'GF' on our packaging stands for Growth Factor MiniProtein™, a next-generation form of growth factor in skincare. Its small molecular size makes it more advanced than traditional options like TGF, EGF, and IGF, allowing it to unlock previously untapped cosmetic effectiveness within the skin's anti-ageing pathways.
Can I use Exo-PDRN Prismatic+ with exfoliating acids?
Yes. Exo-PDRN Prismatic+ can be applied after exfoliating acids. We recommend following with a moisturiser to help support the skin barrier and minimise the risk of any dryness.
Is Exo-PDRN Prismatic+ suitable for dry skin?
Yes. The formula contains hydrating and soothing ingredients, making it suitable for dry skin. Due to its water-light texture, we recommend following with a moisturiser for optimal comfort and results.
Is Exo-PDRN Prismatic+ suitable for oily skin?
Yes. Exo-PDRN Prismatic+ is oil-free and suitable for oily skin types. It delivers an instant healthy glow without leaving skin looking shiny.
Why are you not using spicules like other exosome serums on the market?
Spicules work by creating micro-channels through controlled micro-trauma. We chose not to include spicules as that can be unnecessarily harsh on post-treatment skin. Instead, Exo-PDRN Prismatic+ uses a carefully engineered combination of advanced ingredients to deliver results in a gentler, more comfortable way, without placing unnecessary stress on the skin.
Should I choose Exo-PDRN or Liquid Peptides Advanced MP?
Both formulas are powerhouses and although there are slight overlaps, they focus on different skin goals. They also complement each other perfectly and can be used together in the same routine. Choose Liquid Peptides Advanced MP if your main goal is line-smoothing. It uses dual MiniProteins™ supported by a concentrated peptide complex to specifically target expression lines and build visible wrinkle reduction over time.  Choose Exo-PDRN Prismatic+ if your skin needs comprehensive rejuvenation and vitality. It focuses on recovery and uses next generation PDRN technology and exosomes to support the skin barrier and restore a healthy glow. If you decide to incorporate both into your routine, we recommend layering from thinnest to thickest consistency. In this case, apply Exo-PDRN Prismatic+ first, followed by Liquid Peptides Advanced MP, both morning and evening.
Can I use Exo-PDRN Prismatic+ with Liquid Peptides Advanced MP?
Absolutely. Exo-PDRN Prismatic+ and Liquid Peptides Advanced MP make an ideal age-defying duo. Use Liquid Peptides Advanced MP to target expression lines and build visible wrinkle reduction and Exo-PDRN Prismatic+ to support long-term skin rejuvenation, resilience and recovery.
Can I use Exo-PDRN Prismatic+ with C-Tetra Advanced?
Absolutely. Exo-PDRN Prismatic+ and C-Tetra Advanced make an ideal duo to help improve the skin’s natural recovery mechanisms. Use C-Tetra Advanced to defend against premature skin ageing and achieve accelerated visible skin brightening, and Exo-PDRN Prismatic+ to support long-term skin rejuvenation, resilience and recovery.
Does the 'GF' in GF MiniProtein™ (found in Liquid Peptides Advanced MP, Advanced Pro-Collagen+ Peptide Cream, and Exo-PDRN Prismatic+) stand for Growth Factor?
Yes, the 'GF' on our packaging stands for Growth Factor MiniProtein™, a next-generation form of growth factor in skincare. Its small molecular size makes it more advanced than traditional options like TGF, EGF, and IGF, allowing it to unlock previously untapped cosmetic effectiveness within the skin's anti-ageing pathways.
Exo-PDRN Prismatic+